This course reimagines inquiry-driven instruction by combining the power of the 5Es instructional model with the flexibility of blended learning. Grounded in student-centered design, this model invites students to explore compelling questions and problems through a structured yet adaptable sequence: Engage, Explore, Explain, Elaborate, and Evaluate. Educators will learn how to leverage online and offline learning environments to give students more control over their learning experience, while ensuring progress toward clear, standards-aligned goals. Each stage of the 5Es is brought to life with practical strategies and spotlight lessons focused on student agency and online discussions, helping teachers spark curiosity, deepen learning, and design for meaningful engagement.